Rhodiola (Rhodiola rosea) is a plant that grows in cold parts of Europe and Asia. The root has a long history of use in traditional medicine. Rhodiola is considered an adaptogen. Adaptogens are a class of natural substances that are believed to stimulate the body's resistance to physical, environmental, and emotional stressors. Rhodiola extract might help protect cells from damage and regulate heartbeat. People use rhodiola for fatigue, anxiety, depression, stress, and many other conditions, but there is no good scientific evidence to support any of these uses.